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ADAMTS 5 PROTEIN
Descriptors Found:
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DeCS
Descriptor
English
:
ADAMTS5 Protein
Descriptor
Spanish
:
Proteína ADAMTS5
Descriptor
Portuguese
:
Proteína ADAMTS5
Synonyms
English
:
A Disintegrin And Metalloproteinase With Thrombospondin Motifs 5 Protein
ADAMTS-5 Protein
ADAMTS11 Protein
ADAMTS5 Protease
Aggrecanase-2
ADAMTS 5 Protein
Aggrecanase 2
Tree Number:
D08.811.277.656.675.374.102.500.875
D09.400.430.500.500.875
D12.776.395.033.500.875
D12.776.860.300.085.875
Definition
English
:
An ADAMTS protease that contains two C-terminal
thrombospondin
(TS) motifs. It functions primarily as an aggrecanase, cleaving AGGRECAN in
CARTILAGE
, and may be involved in the destruction of aggrecan in
ARTHRITIS.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56489
Unique Identifier:
D000071116
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS